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KMID : 0357919830170010001
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Korean Journal of Pathology
1983 Volume.17 No. 1 p.1 ~ p.9
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Morphologic Studios on the Endometrium of Abnormal Uterine Bleeding with Special Emphasis on Dysfunctional Uterine Bleeding
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Abstract
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Abnormal uterine bleeding is one of the most common symptoms in gynecologic
disorders of which dysfunctional uterine bleeding (DUB) is frequently encountered.
Although the correct diagnosis of DUB relies on various assessments such as the
menstrual cycle, basal body temperature, endocrine assay, vaginal cytology and
endometrial histologic findings, pathologists knave been encountered in many instances
which have to make a diagnosis on the endometrium only. In view of great difficulties
to make a proper histologic evaluation of endometrium in cased of DUB, the present
study is undertaken to asses the pattern of the endometrium in DUB among Koreans.
The material consisted of 123 cases of endometrial curettage specimens diagnosed as
DUB, among which 17 cases were subjected to total hysterectomy.
Histologic examination was carried out through routine formaline fixed-paraffin
embedding methods followed by hematoxylin-eosin staining routinely and other special
staininga as required. Histologic pattern of the endometriuln was classified according to
Handrickson and Kempson(1980) and clinical correlation was made.
The following results were obtained :
1) The pattern of the endometrium in DUB was predominantly non-secretory type(77
cases) and the secsetory type was observed in 46 cases. Abnormal endometrial histology
was found in 73 cases of which 59 cases was non-secretory and 14 cases secretory
type.
2) The incidence of anovulatory bleeding in DUB was 59%.
3) The bleeding pattern was mostly metrorrhagia but menometrorrhagia was
predominant in cases of hyperplasia.
4) The incidence of recurrent bleeding was 31% and relatively higher in secretory
endometrium.
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